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Image Search Results
Journal: Cellular and Molecular Immunology
Article Title: Human PBMC-transferred murine MHC class I/II-deficient NOG mice enable long-term evaluation of human immune responses
doi: 10.1038/cmi.2017.106
Figure Lengend Snippet: Influenza HA-specific B-cell responses were induced by HA vaccination in the human PBMC-transferred NOG-dKO mice. NOG-dKO mice were intraperitoneally immunized with influenza HA vaccine on the day after intravenous transplantation of human PBMCs. On day 7 and day 14, mice sera were collected and the anti-HA IgG titer was measured by ELISA ( a ). On day 16, the number of anti-HA IgG-producing human B cells collected from mouse spleens were measured by ELISPOT ( b ). The data are representative of three experiments. Each dot indicates an individual mouse ( n =3–4). * P <0.05 ( t -test).
Article Snippet: An avidin-biotin complex method was performed with a
Techniques: Transplantation Assay, Enzyme-linked Immunosorbent Assay, Enzyme-linked Immunospot